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Updated: Nov 15, 2025
Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
Vena Cava and Pancreatic head En Bloc Resection for an Invasive Inferior Vena Cava Leiomyosarcoma in a Liver
Marcos Bettini Pitombo1, Claire Goumard2, Chetana Lim3
1APHP, Unité de Chirurgie Hépatobiliaire et Transplantation Hépatique, Hôpital Universitaire la Pitié Salpêtrière, Paris, France; Department of General Surgery, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Background:
De novo neoplasms are one of the major causes of death in patients after the first year of liver transplantation. The occurrence of sarcomas is extremely rare and the survival is often poor. However, early diagnosis and radical surgical treatment, may benefit some select liver transplant patients.
Method:
We describe the case of a liver transplant patient who developed a locally advanced inferior vena cava (IVC) leiomyosarcoma, who underwent radical surgical treatment with resection of the IVC associated with duodenopancreatectomy, right nephrectomy, and IVC reconstruction. We address aspects of the diagnosis and surgical strategy.
Conclusion:
This case report illustrates that IVC and multivisceral resections may be feasible and safe in highly selected liver transplant recipients. Major surgery should not be excluded as treatment option in an immunosuppressed liver transplant patient.
