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Abdominal Aortic Intima-Media Thickness Predicts Coronary Artery Disease Severity in Patients With Stable Angina

Omer Faruk Cirakoglu1, Ayşe Gül Karadeniz2, Ali Riza Akyüz1

  • 1Department of Cardiology, Trabzon Ahi Evren Training and Research Hospital, University of Health Science, Trabzon, Turkey.

Angiology
|March 5, 2021
PubMed

Insights

Abdominal aortic intima-media thickness (AAIMT) predicts coronary artery disease (CAD) severity. Higher AAIMT levels indicate a greater likelihood of severe CAD, aiding cardiologists in patient management.

Area of Science:

  • Cardiology
  • Vascular Ultrasound
  • Atherosclerosis Research

Background:

  • Accurate identification of coronary artery disease (CAD) is crucial for managing patients with suspected angina.
  • Arterial wall thickening, a marker of atherosclerosis, necessitates understanding early indicators.
  • Abdominal aortic intima-media thickness (AAIMT) represents an early site of atherosclerotic changes.

Purpose of the Study:

  • To evaluate the predictive value of AAIMT for CAD severity.
  • To determine if AAIMT can forecast the extent of coronary artery narrowing.
  • To assess AAIMT as a noninvasive marker in patients with suspected stable angina pectoris.

Main Methods:

  • Prospective study of 255 patients undergoing coronary angiography for suspected stable angina.
  • B-mode ultrasonography utilized to measure AAIMT prior to angiography.
  • Coronary artery disease severity quantified using the SYNTAX score (SS).

Main Results:

  • Higher AAIMT was an independent predictor of intermediate or high SYNTAX scores (odds ratio: 2.570; P < .001).
  • Factors like hypertension, age, and dyslipidemia also predicted higher SS.
  • AAIMT <1.3 mm demonstrated a 98% negative predictive value for intermediate/high SS and 83% for obstructive CAD.

Conclusions:

  • AAIMT independently predicts intermediate or high SYNTAX scores in patients with suspected CAD.
  • AAIMT serves as a valuable, noninvasive tool for cardiologists.
  • This measurement can assist in guiding decisions regarding more invasive diagnostic or therapeutic approaches.

Keywords:
SYNTAX scoreabdominal aortic intima-media thicknessobstructive coronary artery diseasestable angina pectoris

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