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The Effects of Avocado Waste and Its Functional Compounds in Animal Models on Dyslipidemia Parameters

Jessica Elizabeth Pineda-Lozano1, Alma Gabriela Martínez-Moreno1, Carmen Alejandrina Virgen-Carrillo1

  • 1Instituto de Investigaciones en Comportamiento Alimentario y Nutrición (IICAN), Centro Universitario del Sur, Universidad de Guadalajara, Ciudad Guzmán, Mexico.

Frontiers in Nutrition
|March 5, 2021
PubMed

Insights

Avocado waste contains compounds that may improve lipid profiles. This review explores their potential to combat dyslipidemia and reduce heart disease risk in preclinical studies.

Area of Science:

  • Biochemistry
  • Pharmacology
  • Nutritional Science

Background:

  • Ischemic heart disease and stroke are leading causes of mortality globally.
  • Dyslipidemia, characterized by abnormal cholesterol and triglyceride levels, is a major risk factor for cardiovascular diseases.
  • Conventional treatments for dyslipidemia include medications and dietary changes, but natural compounds offer alternative therapeutic avenues.

Purpose of the Study:

  • To review the evidence on the effects of bioactive compounds from avocado waste on dyslipidemia parameters.
  • To identify specific compounds and extraction methods used in preclinical studies.
  • To assess the potential of avocado waste derivatives as a source for managing dyslipidemia.

Main Methods:

  • Systematic literature search for preclinical studies investigating avocado waste extracts.
  • Analysis of extracted compounds and their reported biological activities.
  • Evaluation of studies reporting effects on lipid profiles (cholesterol, triglycerides, HDL, LDL).

Main Results:

  • Avocado waste (peel, seed, leaf) contains compounds with antioxidant and lipid-lowering properties.
  • Preclinical studies demonstrate that these compounds can positively modulate dyslipidemia parameters.
  • Various extraction methods have been employed to isolate bioactive compounds from avocado waste.

Conclusions:

  • Bioactive compounds derived from avocado waste show promise in managing dyslipidemia.
  • Further research is warranted to explore their therapeutic potential for cardiovascular disease prevention.
  • Avocado waste represents a sustainable and valuable source of natural compounds for health applications.

Keywords:
animal modelavocado wastedyslipidemiafunctional compoundsreview

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