Related Experiment Video

Updated: Nov 15, 2025

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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Drug Resistance and Novel Therapies in Cancers in 2019

Zhixiang Wang1

  • 1Signal Transduction Research Group, Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.

Cancers
|March 6, 2021
PubMed

Insights

The "Drug Resistance and Novel Therapies in Cancers" topic collection, launched in 2018, had a productive first full year in 2019. It focused on advancing cancer treatment strategies and understanding drug resistance mechanisms.

Area of Science:

  • Oncology
  • Pharmacology
  • Cancer Research

Background:

  • The topic collection "Drug Resistance and Novel Therapies in Cancers" was launched by *Cancers* in late 2018.
  • 2019 marked the first full year of this collection, demonstrating significant activity and contribution to the field.

Discussion:

  • The collection addresses critical challenges in oncology, specifically the mechanisms of drug resistance.
  • It highlights the development and investigation of novel therapeutic approaches to overcome treatment failures.

Key Insights:

  • Research within the collection focuses on identifying biomarkers for drug resistance.
  • Exploration of innovative drug delivery systems and combination therapies is a key theme.
  • Understanding the tumor microenvironment's role in therapeutic response is emphasized.

Outlook:

  • Continued research is expected to yield new strategies for personalized cancer medicine.
  • The collection aims to foster collaboration and accelerate the translation of findings into clinical practice.
  • Future work will likely explore emerging therapeutic modalities and resistance pathways.

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