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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Asymptomatic Left Ventricular Dysfunction: Is There a Role for Screening in General Population?

Salvatore La Carrubba1, Roberta Manganaro2, Concetta Zito2

  • 1Villa Sofia Hospital, Palermo, Italy.

Heart Failure Clinics
|March 6, 2021
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Early detection of asymptomatic left ventricular dysfunction is crucial for preventing heart failure (HF). Echocardiography is ideal for screening, and new technologies may enhance early detection of cardiac dysfunction.

Keywords:
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Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Stage A and B heart failure (HF) involve asymptomatic individuals, with Stage B characterized by structural cardiac disorders.
  • Asymptomatic left ventricular (LV) dysfunction signifies an early, preclinical stage of HF.
  • Early recognition of LV dysfunction is vital to prevent progression to overt HF.

Purpose of the Study:

  • To highlight the role of echocardiography in screening for early-stage heart failure.
  • To emphasize the importance of detecting asymptomatic left ventricular dysfunction.
  • To explore the potential of novel echocardiographic technologies in identifying early LV dysfunction.

Main Methods:

  • Traditional echocardiography assesses LV systolic and diastolic function and cardiac remodeling.
  • Echocardiography is presented as a feasible, low-cost, and accessible screening tool for the general population.
  • The study discusses the integration of new imaging technologies for enhanced detection.

Main Results:

  • Echocardiography is pivotal for assessing cardiac structure and function.
  • Traditional echocardiographic assessments are standard for evaluating LV function and remodeling.
  • Emerging echocardiographic technologies offer potential for improved detection of early LV dysfunction.

Conclusions:

  • Echocardiography is the preferred imaging technique for screening asymptomatic individuals for early heart failure.
  • Identifying asymptomatic LV dysfunction is key to preventing overt heart failure.
  • Advancements in echocardiography promise to improve the early diagnosis of cardiac dysfunction.