Related Experiment Video
Updated: Nov 15, 2025
09:21
Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
7.4K
A rare case report of breast sarcoma
Nguyen-Van Sang1, Nguyen Minh Duc2,3,4, Thieu-Thi Tra My2
1Department of Radiology, E Hospital, Ha Noi, Vietnam.
Radiology Case Reports
|March 8, 2021
Summary
Breast sarcomas are rare, aggressive cancers originating from mammary gland mesenchymal tissue. This case highlights a patient with undifferentiated pleomorphic breast sarcoma who developed brain and lung metastasis despite treatment.
Area of Science:
- Oncology
- Pathology
Background:
- Breast sarcomas are rare malignant tumors arising from the mammary gland's mesenchymal tissue.
- These tumors are classified as primary or secondary (therapy-related) and are known for their aggressive nature and poor prognosis.
Observation:
- A 51-year-old female presented with a palpable left breast mass and bloody nipple discharge lasting over 4 months.
- Initial presentation suggested a localized tumor requiring surgical intervention.
Findings:
- Postoperative histopathology confirmed an undifferentiated pleomorphic breast sarcoma.
- Despite multimodal treatment including surgery, chemotherapy, and radiotherapy, the patient experienced metastasis to the brain and lungs within 8 months.
Implications:
- This case underscores the aggressive behavior of breast sarcomas and the challenges in managing advanced disease.
- Early detection and aggressive treatment strategies are crucial, but the high risk of metastasis necessitates ongoing surveillance and research into novel therapeutic approaches.
