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Hypertension and COVID-19: Ongoing Controversies
Marijana Tadic1, Sahrai Saeed2, Guido Grassi3
1Department of Cardiology, University Hospital "Dr. Dragisa Misovic - Dedinje", Belgrade, Serbia.
Frontiers in Cardiovascular Medicine
|March 8, 2021
Summary
Hypertension is a significant risk factor for severe outcomes in Coronavirus disease 2019 (COVID-19). This review clarifies the impact of blood pressure, antihypertensive therapies, and hypertension diagnosis on COVID-19 patient prognosis.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic with significant mortality.
- Hypertension is a prevalent comorbidity associated with severe COVID-19 outcomes.
- The independent predictive value of hypertension in COVID-19 requires further clarification.
Purpose of the Study:
- To review the clinical evidence on hypertension as a predictor of COVID-19 severity and outcomes.
- To examine the influence of blood pressure levels and antihypertensive treatments on COVID-19 prognosis.
- To assess the impact of both chronic and newly diagnosed hypertension in COVID-19 patients.
Main Methods:
- Systematic literature review of studies investigating hypertension and COVID-19 outcomes.
- Analysis of data concerning blood pressure, comorbidities, and antihypertensive medications.
- Synthesis of evidence on the predictive value of hypertension in diverse patient populations.
Main Results:
- Hypertension is consistently linked to increased severity and adverse outcomes in COVID-19 patients.
- Blood pressure levels and specific antihypertensive therapies (ACEI/ARB) show complex associations with COVID-19 prognosis.
- Both pre-existing and newly diagnosed hypertension are critical factors influencing COVID-19 patient management and outcomes.
Conclusions:
- Hypertension is a crucial independent risk factor for severe COVID-19.
- Understanding the interplay between hypertension, blood pressure management, and COVID-19 is vital for clinical practice.
- Further research is needed to optimize treatment strategies for hypertensive patients with COVID-19.
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