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Fossilized Teeth as a New Robust and Reproducible Standard for Polarization-Sensitive Optical Coherence Tomography.

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Summary

Fossilized Megalodon shark and horse teeth offer a cheap, repeatable standard for polarization sensitive optical coherence tomography (PS-OCT) calibration, reducing measurement errors.

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Area of Science:

  • Biomedical Optics
  • Paleontology
  • Materials Science

Background:

  • Polarization sensitive optical coherence tomography (PS-OCT) requires reliable calibration standards.
  • Existing standards can be expensive or lack microstructural consistency.

Purpose of the Study:

  • To evaluate the utility of fossilized shark and horse teeth as a cost-effective and robust standard for PS-OCT.
  • To assess the repeatability and accuracy of these fossilized teeth for birefringence measurements.

Main Methods:

  • Fossilized Megalodon shark and European horse teeth were used as calibration standards.
  • Birefringence values were measured, and maximum differences were analyzed.
  • Measurements were compared to those of biological tissues (bovine meniscus, tendon) verified by histology.

Main Results:

  • Fossilized teeth demonstrated fast and repeatable birefringence measurements.
  • The microstructural consistency of fossilization provided reliable calibration.
  • The fossilized teeth standard effectively reduced errors from factors like catheter bending and temperature fluctuations.

Conclusions:

  • Prehistoric fossilized teeth are a viable, inexpensive, and robust standard for PS-OCT.
  • This novel approach enhances the accuracy and efficiency of PS-OCT calibration in clinical settings.