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Volumetric PET parameters are predictive for the prognosis of locally advanced cervical cancer
Adnan Budak1, Emine Budak2, Ahkam G Kanmaz1
1Department of Obstetrics and Gynecology, Tepecik Hospital, Izmir, Türkiye.
Background:
The present study evaluates the relationship between PET/CT findings and survival in patients with locally advanced cervical cancer (LACC) with a squamous cell histology.
Methods:
The study included 70 patients with LACC (FIGO stage IB2-IVA). The relationship between pretreatment PET/CT parameters, age, stage, lymph node metastasis and survival was evaluated using the univariate and multivariate Cox proportional hazards model.
Results:
The mean age of the 70 patients was 57.4 years and the mean duration of follow-up was 33.6 months. Disease progression occurred in 36 patients and 32 patients died during the follow-up period. In the univariate analysis, MTV-P and TLG-P were found to be related to progression-free survival (PFS), and stage, MTV-P, TLG-P and SUV
Conclusions:
The present findings suggest that volumetric PET parameters (MTV-P, TLG-P) predict the progression and survival of the patients with LACC.
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