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Updated: Nov 14, 2025

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
Published on: April 19, 2024
Open and Closed Endotracheal Suction Systems Divergently Affect Pulmonary Function in Mechanically Ventilated
Rodrigo Daminello Raimundo1, Monica Akemi Sato1, Talita Dias da Silva2,3,4
1Laboratório de delineamento de estudos e escrita científica, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil.
Open suction systems (OSS) may increase airway resistance and peak inspiratory pressure more than closed suction systems (CSS) in mechanically ventilated patients. This suggests CSS may be preferable for patients with elevated airway resistance to prevent pulmonary injury.
Area of Science:
- Critical Care Medicine
- Respiratory Therapy
- Pulmonary Physiology
Background:
- Mechanically ventilated patients require airway suctioning using open (OSS) or closed suction systems (CSS).
- OSS involves ventilator disconnection, potentially reducing positive end-expiratory pressure (PEEP) and oxygen supply.
- CSS is more expensive and may be less effective for secretion removal.
Purpose of the Study:
- To compare the effects of OSS and CSS on cardiorespiratory parameters in mechanically ventilated subjects.
- To determine if suction system choice impacts pulmonary and cardiovascular stability.
Main Methods:
- A crossover design study involving 66 ICU subjects.
- Subjects were quasi-randomized to initial treatment with either OSS or CSS.
- Cardiopulmonary physiology was assessed before and after three 10-second aspirations with each system.
Main Results:
- Most cardiopulmonary parameter changes correlated inversely with baseline values, with similar slopes for both systems.
- Open suction systems (OSS) resulted in significantly greater increases in airway resistance and peak inspiratory pressure compared to closed suction systems (CSS) when controlling for baseline values.
Conclusions:
- Patients with elevated airway resistance may benefit from CSS, while conventional OSS might be contraindicated.
- Implementing this approach in clinical guidelines could help prevent suction-induced pulmonary injury, particularly in patients with pre-existing airway resistance or alveolar pressure issues.
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