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Evaluation of Reparative Dentine Bridge Formation after Direct Pulp Capping with Biodentine
Anh Huynh Bui1, Khoa Van Pham1
1Department of Operative Dentistry and Endodontics, Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.
Summary
Biodentine effectively promotes reparative dentin bridge formation in direct pulp capping procedures for permanent teeth. Cone-beam computed tomography (CBCT) scans reliably assessed this dentin bridge formation.
Area of Science:
- Dental Materials Science
- Regenerative Dentistry
- Endodontics
Background:
- Direct pulp capping aims to preserve pulp vitality.
- Biodentine is a calcium-silicate based material used in restorative dentistry.
- Evaluating new materials for direct pulp capping is crucial for tooth preservation.
Purpose of the Study:
- To assess Biodentine's efficacy for direct pulp capping in permanent teeth.
- To evaluate the formation of reparative dentin after Biodentine application.
- To determine the reliability of imaging modalities for assessing dentin bridge formation.
Main Methods:
- 11 human premolars underwent mechanical pulp exposure and direct pulp capping with Biodentine.
- Teeth were evaluated clinically and radiographically (intraoral radiograph and CBCT) at baseline and 9-12 weeks post-treatment.
- Reparative dentin bridge formation was assessed in both in vivo and ex vivo settings.
Main Results:
- Histological analysis confirmed reparative dentin bridge formation in all teeth treated with Biodentine.
- Both intraoral radiography and CBCT imaging demonstrated dentin bridge formation.
- Clinical symptoms and signs were recorded throughout the observation period.
Conclusions:
- Biodentine demonstrates a capability to induce reparative dentin formation in direct pulp capping.
- Cone-beam computed tomography (CBCT) is a reliable imaging technique for evaluating dentin bridge formation after direct pulp capping.
- Biodentine shows promise as a material for direct pulp capping in permanent teeth.

