Related Experiment Video
Updated: Nov 14, 2025

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
[Sjögren's syndrome: from diagnosis to treatment]
Alexandre Dumusc1, Camillo Ribi2
1Service de rhumatologie, Département de l'appareil locomoteur, CHUV, 1011 Lausanne.
Abstract:
Sjögren's syndrome (SS) is an auto-immune condition involving salivary and lacrymal glands leading to dry mouth and dry eyes symptoms. Some patients also present with systemic manifestations. Diagnosis of SS is made after clinical, serological, and histological assessment according to the American College of Rheumatology and European League Against Rheumatism (EULAR) classification criteria. Recent clinical trials showed a significant decrease of systemic activity of SS in patients treated with iscalimab (anti-CD40) and ianalumab (anti-BAFF-R). These results need to be confirmed in larger studies. However, two phase 3 randomized trials did not show efficacy treating SS with abatacept. We also describe in this article the first EULAR recommendations on SS management.
More Related Videos
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
Nephrotic Syndrome I : Introduction
Nephrotic Syndrome III : Nursing Management
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

