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Meningeal lymphatics prime tumor immunity in glioblastoma
Maya S Graham1, Ingo K Mellinghoff2
1Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Cancer Cell
|March 10, 2021
Abstract:
The notion of the brain as an immune-privileged organ has been challenged by the discovery of functional lymphatic vessels in the meninges of the dorsal and basal skull. A study published in Nature in 2020 shows that meningeal lymphatics play an important role in the sensing of brain tumor antigens.
