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Aortic Thrombosis in the Course of Covid-19 Disease; Two Rare Cases

Ahmet Rıfkı Çora1, Ersin Çelik1, Kadir Burhan Karadem2

  • 1Isparta City Hospital Cardiovascular Surgery Clinic, Isparta, Turkey.

Annals of Vascular Surgery
|March 10, 2021
PubMed

Insights

Severe COVID-19 can cause aortic thrombosis, a rare but deadly vascular complication. This study highlights two fatal cases, emphasizing the need to consider aortic thrombosis in affected patients with circulatory issues.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Cardiology

Background:

  • Acute aortic thrombosis and aortoiliac thrombus are rare conditions associated with high mortality.
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, or COVID-19, can induce a hyperinflammatory and hyperimmune state.
  • This state may lead to hypercoagulability and subsequent thrombotic events.

Observation:

  • Two COVID-19 positive patients presented with rare aortic thrombotic events.
  • Diagnostic computerized tomographic angiography revealed total aortic thrombosis below the renal arteries in one patient and a floating aortic thrombus in the other.
  • Both patients experienced clinical deterioration despite initial medical management.

Findings:

  • Despite medical therapies, both patients died before surgical intervention could be performed.
  • The cases illustrate a severe thrombotic complication of COVID-19 affecting the vascular system.

Implications:

  • COVID-19 impacts not only the pulmonary and inflammatory systems but also the coagulation and vascular systems.
  • Aortic thrombosis should be considered in COVID-19 patients presenting with impaired peripheral circulation.
  • Early recognition and management strategies for vascular complications in COVID-19 patients are crucial.
Abstract

Keywords:
Aortic ThrombusCovid-19Hypercoagulability

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