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Enhancing the sensitivity of a transmissive graphene-based plasmonic biosensor
Applied Optics
|March 10, 2021
Summary
This study introduces a graphene-based terahertz biosensor for enhanced molecule detection. By optimizing graphene layers and substrate, sensitivity significantly improved, paving the way for advanced biosensing applications.
Area of Science:
- Plasmonics
- Terahertz (THz) biosensing
- Graphene-based nanodevices
Background:
- Terahertz (THz) biosensors offer label-free detection of biomolecules.
- Graphene's unique properties can enhance THz wave interactions.
- Improving sensitivity in THz biosensing remains a key challenge.
Purpose of the Study:
- To design and investigate a novel graphene-based biosensor platform operating in the terahertz range.
- To enhance the sensitivity of a THz biosensor through structural modifications.
- To explore the impact of graphene layering and substrate material on biosensor performance.
Main Methods:
- Development of a nanofluidic channel biosensor with a graphene patch and grounded graphene layers.
- Simulation and analysis of scattering parameters to detect molecular presence.
- Systematic variation of graphene sheet numbers and substrate materials (Silicon, Silica).
- Investigation of sensor response to changes in the refractive index of the sensing layer.
Main Results:
- Increasing the number of graphene sheets significantly enhances absorption and sensitivity.
- A maximum sensitivity of 8470 nm/RIU was achieved by inserting a graphene sheet between two others.
- Further sensitivity enhancement to 15410 nm/RIU was observed when using a silica substrate with three graphene sheets.
Conclusions:
- The proposed graphene-based THz biosensor architecture demonstrates significantly improved sensitivity.
- Optimizing graphene configuration and substrate material are crucial for high-performance THz biosensing.
- This work presents a promising platform for sensitive and label-free detection of biomolecules.

