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Hemichorea Neglect after Stroke.

Yosuke Aiba1, Ryuji Sakakibara1, Tsuyoshi Ogata1

  • 1Neurology, Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.

Case Reports in Neurology
|March 12, 2021
PubMed
Summary
This summary is machine-generated.

A rare case of right hemichorea and neglect followed left thalamic infarction in a 74-year-old woman. Brain imaging revealed perfusion changes, suggesting de-afferentiation as a cause.

Keywords:
HemichoreaNeglectStriatumStroke

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Area of Science:

  • Neurology
  • Neuroscience
  • Radiology

Background:

  • Thalamic infarction is a stroke affecting the thalamus, a key relay center in the brain.
  • Hemichorea is an involuntary, irregular, and jerky movement disorder affecting one side of the body.
  • Neglect is a neurological disorder where patients are unaware of one side of space.

Observation:

  • A 74-year-old Japanese woman experienced right hemichorea and neglect after a left thalamic infarction.
  • Neuroimaging demonstrated altered brain perfusion in both ipsilateral and contralateral areas.

Findings:

  • The observed symptoms and perfusion changes suggest a link between thalamic damage and subsequent movement and spatial awareness deficits.
  • De-afferentiation, a loss of sensory input, is hypothesized as the underlying mechanism for these neurological alterations.

Implications:

  • This case highlights the complex relationship between thalamic function and motor control, as well as spatial attention.
  • Understanding these mechanisms can inform future therapeutic strategies for stroke recovery and movement disorders.
  • Further research into thalamic connectivity and de-afferentiation is warranted to elucidate these neurological phenomena.