Related Experiment Video
Updated: Nov 14, 2025

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
Published on: May 26, 2023
Cardiovascular protection effect of chlorogenic acid: focus on the molecular mechanism
Mifetika Lukitasari1, Mohammad Saifur Rohman2, Dwi Adi Nugroho3
1Department of Nursing, Faculty of Medicine, Brawijaya University, Malang, East java, +62, Indonesia.
Abstract:
Vascular endothelial cells have a variety of functions such as the control of blood coagulation, vascular permeability, and tone regulation, as well as quiesce of immune cells. Endothelial dysfunction is a cardiovascular events predictor, which is considered the initial stage in atherosclerosis development. It is characterized by alterations in endothelium functions due to imbalanced vasodilators and vasoconstrictors, procoagulant and anticoagulant mediators, as well as growth inhibitor and promotor substances. Chlorogenic acid (CGA) is the primary polyphenol in coffee and some fruits. It has many health-promoting properties, especially in the cardiovascular system. Many studies investigated the efficacy and mechanism of this compound in vascular health. CGA has several vascular benefits such as anti-atherosclerosis, anti-thrombosis, and anti-hypertensive. This review focuses on the molecular mechanism of CGA in vascular health.
More Related Videos
Related Concept Videos
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease II: Pathophysiology
Atherosclerosis III: Management
Cholesterol: Significance and Regulation
Considering cholesterol and...
Protecting Groups for Aldehydes and Ketones: Introduction

