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Updated: Nov 13, 2025

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Distraction Osteogenesis in Craniofacial Surgery: Past, Present, and Future
Petros Konofaos1, Robert D Wallace
1Department of Plastic Surgery, University of Tennessee Health Science Center, Memphis, TN.
Abstract:
Distraction osteogenesis (DO) is considered one of the treatments of choice for the surgical correction of malformations of the craniofacial skeleton. This is due to its ability to generate bone at the distraction site along with the accompanying soft tissue changes, the possibility to combine DO with traditional orthognathic procedures and the successful reported long-term outcomes following its application to various craniofacial deformities. The aim of this review is to present an overview of the literature on the evolution of DO applications in craniofacial surgery through the last 35 years.
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