[Machine learning and multiparametric MRI for early diagnosis of prostate cancer]

In the last few years, the early diagnosis of prostate cancer has continued to shift from systematic biopsies to multiparametric MRI (mpMRI)-guided/MRI-transrectal ultrasound (TRUS) fusion biopsies and guidelines are already reflecting these changes. While MRI-TRUS fusion biopsies have already resulted in significant improvements in diagnostic sensitivity and, thus, correct diagnosis of clinically significant prostate cancer (sPC), its use to avoid biopsies in certain men is still controversial. Optimal use of mpMRI requires a high degree of reader expertise due to the difficulty of image interpretation and poses the problem of training sufficient numbers of radiologists while demand is increasing. Recently, artificial intelligence (AI) has been utilized to create fully automatic analysis tools for interpretation of mpMRI of the prostate, rivaling the performance of clinical radiologist interpretation in retrospective research studies, demonstrating the promising potential of AI for diagnostic prostate MRI in the future. This article will provide an overview of machine and deep learning and its application in mpMRI of the prostate for early diagnosis of prostate cancer.