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Updated: Nov 13, 2025
08:45
Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
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Tako-tsubo syndrome and hypovolemia
Olga Vriz1, Rodolfo Citro2, Stefano Martina1
1U.O. Cardiologia/Terapia Intensiva, San Antonio Hospital, San Daniele del Friuli (UD). ebossone@hotmail.com.
Summary
Tako-tsubo syndrome (TTS), a stress-induced heart condition, can be linked to low blood volume and sodium levels. This case highlights how hypovolemia may trigger TTS through sympathetic nervous system activation.
Area of Science:
- Cardiology
- Internal Medicine
- Pathophysiology
Background:
- Tako-tsubo syndrome (TTS) is a reversible heart condition.
- It often mimics acute myocardial infarction.
- Stress is a common trigger for TTS.
Purpose of the Study:
- To describe a case of TTS in an elderly woman.
- To explore the association between TTS, hypovolemia, and hyponatremia.
- To investigate the potential pathophysiological mechanism linking hypovolemia to TTS.
Main Methods:
- Case report of a 78-year-old female patient.
- Clinical assessment for Tako-tsubo syndrome.
- Evaluation of electrolyte and volume status.
Main Results:
- The patient presented with TTS.
- Associated conditions included hypovolemia and hyponatremia.
- Hypovolemia is hypothesized to activate the sympathetic system, leading to catecholamine overload and myocardial stunning.
Conclusions:
- Hypovolemia and hyponatremia can be associated with Tako-tsubo syndrome.
- The sympathetic nervous system and catecholamine overload may play a role in TTS development.
- Further research is needed to elucidate the relationship between volume status and TTS pathophysiology.
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