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[Pentoxyverine poisoning via maternal milk in a fully breast-fed newborn infant]
B J Stier1, L Sieverding, H Moeller
1Kinderklinik der Universität Tübingen.
A four-week-old male infant who had been exclusively breast-fed by his mother developed acute respiratory failure with intermittent arrest of breathing for up to 15 sec, in between sighing breaths and normal ones. For two weeks his mother had been taking pentoxyverine-containing cough drops for an upper respiratory tract infection. Pentoxyverine was demonstrated in maternal serum and breast milk, as well as the child's serum and urine, in some in very high concentrations. The course of the illness and comparison with reported instances of pentoxyverine poisoning in infants makes it likely that this, too, was such a case.
A four-week-old male infant who had been exclusively breast-fed by his mother developed acute respiratory failure with intermittent arrest of breathing for up to 15 sec, in between sighing breaths and normal ones. For two weeks his mother had been taking pentoxyverine-containing cough drops for an upper respiratory tract infection. Pentoxyverine was demonstrated in maternal serum and breast milk, as well as the child's serum and urine, in some in very high concentrations. The course of the illness and comparison with reported instances of pentoxyverine poisoning in infants makes it likely that this, too, was such a case.