Children hospitalised with four common viral diseases showed epidemiological differences but few socio-economic

Katarina Widgren1,2, Margareta Eriksson3, Rutger Bennet3

  • 1Department of Medicine, Huddinge, Karolinska Institute, Stockholm, Sweden.

Insights

Differences in demographic factors were found among children hospitalized for rotavirus, influenza, respiratory syncytial virus (RSV), and chickenpox. These variations are primarily linked to the specific epidemiology and transmission patterns of each viral infection.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Common viral infections in children necessitate hospitalisation.
  • Understanding demographic and socio-economic disparities among hospitalised children is crucial for targeted public health interventions.

Purpose of the Study:

  • To investigate demographic and socio-economic differences in children hospitalised with four common viral infections: rotavirus, influenza, respiratory syncytial virus (RSV), and chickenpox.
  • To compare these factors between different viral infection case groups.

Main Methods:

  • Utilised demographic data from Statistics Sweden for over 3000 children admitted to Astrid Lindgren Children's Hospital between 2009-2014.
  • Employed logistic regression analysis, using rotavirus cases as the reference group, to compare demographic and socio-economic factors.

Main Results:

  • Significant differences in median age at admission were observed: RSV cases were youngest (0.4 years), followed by rotavirus (1.2 years), influenza (2.4 years), and chickenpox (2.7 years).
  • Children hospitalised with RSV, influenza, and chickenpox were more likely to come from larger families compared to rotavirus cases.
  • RSV and influenza cases showed a higher prevalence of underlying chronic conditions, and mothers of RSV cases were more frequently born in Sweden. Socio-economic differences were not consistently confirmed.

Conclusions:

  • Identified several demographic variations among children hospitalised for the four common viral infections.
  • These observed differences are largely attributable to the distinct epidemiological and transmission characteristics of each infection.
Abstract

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