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8-Channel Biphasic Current Stimulator Optimized for Retinal Prostheses.

Chae-Eun Lee1, Younginha Jung1, Yoon-Kyu Song1

  • 1Department of Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea.

Journal of Nanoscience and Nanotechnology
|March 14, 2021
PubMed
Summary
This summary is machine-generated.

This study presents an 8-channel neural stimulator for retinal prostheses, designed to electrically stimulate retinal ganglion cells (RGCs) with high spatial resolution. The device is optimized for efficiency and safety in retinal implantation.

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Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Electrical Engineering

Background:

  • Retinal prostheses aim to restore vision by electrically stimulating retinal ganglion cells (RGCs) to compensate for damaged photoreceptors.
  • High spatial resolution is crucial for effective RGC stimulation due to their dense packing, leading to increased microelectrode impedance.
  • Current-source-based stimulators require high output impedance and high compliance voltage for effective retinal implantation.

Purpose of the Study:

  • To design and fabricate a customized 8-channel neural stimulator for retinal ganglion cell (RGC) stimulation.
  • To address the challenges of high spatial resolution and impedance in retinal prostheses.
  • To optimize stimulation parameters for efficiency and safety in retinal implants.

Main Methods:

  • Design of an 8-channel neural stimulator IC.
  • Fabrication using TSMC 0.18 μm 1P6M RF CMOS process.
  • Integration of high output impedance and high compliance voltage characteristics.

Main Results:

  • Successful design and fabrication of a specialized 8-channel neural stimulator.
  • The IC occupies a compact area of 1060 μm×950 μm.
  • Operates with a 3.3 V supply voltage, suitable for implantable devices.

Conclusions:

  • The developed neural stimulator is tailored for RGC stimulation, addressing key challenges in retinal prosthesis design.
  • The design emphasizes high spatial resolution and efficient electrical stimulation.
  • This work contributes to the advancement of implantable neuroprosthetics for vision restoration.