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Reducing Radiation-Induced Cognitive Toxicity: Sparing the Hippocampus and Beyond

Kristin J Redmond1, Michael T Milano2, Michelle M Kim3

  • 1Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.

International Journal of Radiation Oncology, Biology, Physics
|March 14, 2021
PubMed
Summary

No abstract available in PubMed .

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The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
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