Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Molecular Kinetic Energy01:21

Molecular Kinetic Energy

5.3K
The word "gas" comes from the Flemish word meaning "chaos," first used to describe vapors by the chemist J. B. van Helmont. Consider a container filled with gas, with a continuous and random motion of molecules. During collisions, the velocity component parallel to the wall is unchanged, and the component perpendicular to the wall reverses direction but does not change in magnitude. If the molecule’s velocity changes in the x-direction, then its momentum is changed.
5.3K
Kinetic Molecular Theory: Molecular Velocities, Temperature, and Kinetic Energy03:07

Kinetic Molecular Theory: Molecular Velocities, Temperature, and Kinetic Energy

29.0K
The kinetic molecular theory qualitatively explains the behaviors described by the various gas laws. The postulates of this theory may be applied in a more quantitative fashion to derive these individual laws.
29.0K
SN2 Reaction: Kinetics02:14

SN2 Reaction: Kinetics

9.5K
Kinetic Studies and Significance
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a...
9.5K
SN1 Reaction: Kinetics02:05

SN1 Reaction: Kinetics

8.9K
In an SN2 reaction, the reaction rate depends on both the type of nucleophile and the substrate. A hindered tertiary alkyl halide is practically inert to the SN2 mechanism despite using a strong nucleophile.
However, Sir Christopher Ingold and Edward D. Hughes, who studied the kinetics of various nucleophilic substitution reactions, noticed that a tertiary alkyl halide does undergo a nucleophilic substitution reaction in the presence of a weak nucleophile. While studying the substitution...
8.9K
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

9.1K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
9.1K
Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision02:43

Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision

36.0K
The ideal-gas equation, which is empirical, describes the behavior of gases by establishing relationships between their macroscopic properties. For example, Charles’ law states that volume and temperature are directly related. Gases, therefore, expand when heated at constant pressure. Although gas laws explain how the macroscopic properties change relative to one another, it does not explain the rationale behind it.
36.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trehalose-Functionalized Magnetic Affinity Probe Provides Biochemical Evidence of Nanoparticle Internalization in Mycobacteria.

ACS infectious diseases·2025
Same author

Odd-Even Effects Leading to Alternating Polymerization and Macrocyclization in Nitroaldol Reaction Systems.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Antimicrobial Potency of Nor-Pyochelin Analogues and Their Cation Complexes against Multidrug-Resistant Pathogens.

ACS infectious diseases·2024
Same author

Interdependent Dynamic Nitroaldol and Boronic Ester Reactions for Complex Dynamers of Different Topologies.

Chemistry (Weinheim an der Bergstrasse, Germany)·2024
Same author

Click-free imaging of carbohydrate trafficking in live cells using an azido photothermal probe.

Science advances·2024
Same author

Antimicrobial Delivery Using Metallophore-Responsive Dynamic Nanocarriers.

ACS applied bio materials·2024
Same journal

Transition Metals Catalyzed Element-Cyano Bonds Activations.

Catalysis reviews, science and engineering·2015
See all related articles

Related Experiment Video

Updated: Nov 13, 2025

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
06:48

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

4.6K

Dynamic Covalent Kinetic Resolution.

Yan Zhang1, Yang Zhang2, Olof Ramström3,4

  • 1Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, 214122, P.R. China.

Catalysis Reviews, Science and Engineering
|March 15, 2021
PubMed
Summary
This summary is machine-generated.

Dynamic covalent kinetic resolution (DCKR) offers an efficient strategy for synthesizing enantioenriched compounds. This method uses reversible covalent reactions for substrate racemization, enabling high yields and enantioselectivity in asymmetric synthesis.

Keywords:
Asymmetric synthesisDynamic covalent chemistryDynamic kinetic resolutionEnzymatic catalysisOrganocatalysis

More Related Videos

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
10:54

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR

Published on: February 23, 2016

10.9K
Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.7K

Related Experiment Videos

Last Updated: Nov 13, 2025

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
06:48

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

4.6K
Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
10:54

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR

Published on: February 23, 2016

10.9K
Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.7K

Area of Science:

  • Organic Chemistry
  • Asymmetric Synthesis
  • Catalysis

Background:

  • Dynamic Kinetic Resolution (DKR) is a powerful strategy for creating enantioenriched compounds.
  • Dynamic covalent chemistry provides a versatile platform for DKR, leading to Dynamic Covalent Kinetic Resolution (DCKR).

Purpose of the Study:

  • To review the development of DCKR systems.
  • To highlight the applications of DCKR in asymmetric synthesis and catalysis.

Main Methods:

  • Utilizing reversible covalent reactions for substrate racemization.
  • Employing enzymes or chiral catalysts for the asymmetric transformation step.

Main Results:

  • DCKR systems achieve high yields (>50%) and excellent enantiomeric excesses (ee).
  • DCKR enables efficient interconversion of substrate enantiomers without metal catalysts or racemases.

Conclusions:

  • DCKR is a highly effective approach for synthesizing enantioenriched molecules.
  • The review details various DCKR systems and their synthetic applications.