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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Updated: Nov 12, 2025

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
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Deep model-based magnetic resonance parameter mapping network (DOPAMINE) for fast T1 mapping using variable flip

Yohan Jun1, Hyungseob Shin1, Taejoon Eo1

  • 1School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.

Medical Image Analysis
|March 15, 2021
PubMed
Summary
This summary is machine-generated.

DOPAMINE, a novel deep learning network, significantly accelerates quantitative magnetic resonance (MR) parameter mapping. This method reconstructs MR parameter maps from undersampled data, reducing scan times for clinical applications.

Keywords:
Deep learningMagnetic resonance imagingParameter mappingVariable flip angle

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence in Medicine
  • Biomedical Engineering

Background:

  • Quantitative magnetic resonance (MR) parameter mapping provides crucial diagnostic information.
  • Current methods require long scan times, hindering clinical adoption.
  • Accelerating quantitative MR parameter mapping is essential for real-world applications.

Purpose of the Study:

  • To develop a fast and accurate method for MR parameter mapping.
  • To introduce DOPAMINE, a deep model-based network for reconstructing MR parameter maps from undersampled k-space data.
  • To reduce the acquisition time for quantitative MR parameter mapping.

Main Methods:

  • Proposed DOPAMINE, a hybrid deep learning and model-based network.
  • DOPAMINE utilizes a CNN for initial parameter map estimation (CNN-based mapping).
  • A reconstruction network with a deep CNN and data consistency layer refines parameter maps, removing aliasing artifacts.

Main Results:

  • DOPAMINE demonstrated superior performance in T1 map reconstruction compared to conventional and deep learning methods.
  • Outperformed methods across various reduction factors (R=3, 5, 7) and sampling patterns (1D Cartesian, 2D Poisson-disk).
  • Achieved quantitatively and qualitatively superior MR parameter map reconstruction from undersampled data.

Conclusions:

  • DOPAMINE effectively reduces scan time for quantitative MR parameter mapping using a variable flip angle (VFA) model.
  • The proposed method enables faster acquisition of valuable diagnostic information.
  • DOPAMINE shows significant potential for clinical translation of quantitative MR imaging.