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Updated: Nov 12, 2025

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
Published on: March 20, 2021
Quantification of biomarker functionality predicts patient outcomes
Banafshé Larijani1,2,3, James Miles4,5,6,7, Stephen G Ward8
1FASTBASE Solutions S.L., Kabi 612 Scientific and Technology Park of Bizkaia, Derio, 48160, Spain. bl666@bath.ac.uk.
Abstract:
Implementation of a quantitative molecular imaging method (iFRET), which determines receptor-ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.
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