Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymer Classification: Architecture01:14

Polymer Classification: Architecture

3.4K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
3.4K
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

4.0K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of an electronic nose to characterize geosmin and 2-methylisoborneol of water collected from different phases in water treatment plants.

Water research·2026
Same author

Immune-Inflammatory markers and heart failure incidence and mortality: a population-based longitudinal study.

Frontiers in cardiovascular medicine·2026
Same author

Three-stage interpretability analysis of influenza virus and meteorological correlation in Jiuquan City, 2016-2025: SARIMAX + TreeSHAP.

Frontiers in cellular and infection microbiology·2026
Same author

Recurrent spontaneous abortion: integrated bioinformatics and histological validation identify FURIN and NEDD4 as ferroptosis-associated endometrial markers.

Human immunology·2026
Same author

Compartmentalized co-delivery of CD73 (ecto-5'-nucleotidase) mRNA and rotenone using pH/ROS dual-responsive microgels for neuroinflammation therapy.

International journal of biological macromolecules·2026
Same author

Single-nucleus epigenomic dysregulation unmasks genetic risk-associated neurodegenerative glia states.

Nature communications·2026

Related Experiment Video

Updated: Nov 12, 2025

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.4K

Surface modification by poly(ethylene glycol) with different end-grafted groups: Experimental and theoretical study.

Xia Han1, Zhaobin Yuan1, Yapeng Niu2

  • 1Key Laboratory for Advanced Materials and School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, People's Republic of China.

Biointerphases
|March 17, 2021
PubMed
Summary

Dihydroxyphenylalanine (DOPA) anchors polymers to surfaces, enhancing antifouling properties. DOPA-modified surfaces show superior protein resistance compared to thiol or hydroxyl anchors, confirmed by experiments and theory.

More Related Videos

Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants
11:32

Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants

Published on: December 23, 2013

12.1K
Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry
06:56

Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry

Published on: June 10, 2018

25.8K

Related Experiment Videos

Last Updated: Nov 12, 2025

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.4K
Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants
11:32

Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants

Published on: December 23, 2013

12.1K
Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry
06:56

Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry

Published on: June 10, 2018

25.8K

Area of Science:

  • Biomaterials Science
  • Surface Chemistry
  • Polymer Science

Background:

  • Dihydroxyphenylalanine (DOPA) is a known surface-independent anchor for bioadhesives and antifouling materials.
  • Mechanisms of DOPA adsorption and comparisons with experimental/theoretical data are underexplored.

Purpose of the Study:

  • To investigate the adsorption mechanisms of DOPA-anchored polymers on various substrates.
  • To compare the antifouling performance of DOPA-anchored polymers with thiol and hydroxyl-anchored counterparts.
  • To correlate surface wettability and polymer flexibility with fouling resistance.

Main Methods:

  • Synthesized and characterized DOPA-anchored mPEG (DOPA-mPEG), mPEG-SH, and mPEG-OH.
  • Studied adsorption on gold and hydroxylated silicon substrates.
  • Evaluated protein adsorption resistance and surface wettability.
  • Performed ab initio calculations for adsorption binding energies.

Main Results:

  • DOPA-mPEG exhibited higher affinity for both gold and silicon surfaces compared to mPEG-SH and mPEG-OH.
  • DOPA-mPEG modified surfaces demonstrated superior resistance to protein adsorption.
  • Surface wettability was identified as the primary factor in surface fouling, with polymer flexibility as a secondary factor.
  • Theoretical calculations supported experimental findings, showing favored adsorption of DOPA-mEG due to specific interactions.

Conclusions:

  • DOPA is an effective anchor for creating antifouling surfaces with enhanced protein resistance.
  • The DOPA anchor provides superior surface affinity and antifouling properties compared to traditional thiol and hydroxyl anchors.
  • Understanding adsorption mechanisms and surface properties is crucial for designing advanced biomaterials.