Related Experiment Video
Updated: Nov 12, 2025

08:23
Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
Published on: August 31, 2013
13.4K
Scurvy, Starvation, and Flea Infestation - A Case Report From 21st Century Europe
Alexandra Esteves1, Francisco Teixeira da Silva1, José Carvalho1
1Internal Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
Cureus
|March 17, 2021
Summary
Scurvy, a vitamin C deficiency disease, is often overlooked. This case highlights the importance of recognizing its classic signs and symptoms for timely diagnosis and treatment.
Area of Science:
- Internal Medicine
- Dermatology
- Nutritional Science
Background:
- Scurvy, caused by vitamin C deficiency, is historically linked to malnutrition during voyages, famine, or war.
- Modern physicians may underdiagnose scurvy, viewing it as a historical ailment.
- Recognizing social factors and classic symptoms is crucial for identifying this underreported condition.
Observation:
- A 79-year-old female presented with pruritus, poor hygiene, and a scarce diet.
- Initial symptoms included flea bites, skin lesions, microcytic anemia, and emaciation.
- Later, ecchymosis and perifollicular petechiae indicated potential bleeding issues.
Findings:
- Laboratory analysis revealed undetectable serum vitamin C levels.
- The patient was diagnosed with scurvy based on clinical presentation and low vitamin C.
- Treatment with high-dose oral vitamin C led to complete recovery.
Implications:
- This case underscores the necessity of early recognition and vitamin C supplementation for scurvy.
- Physicians must remain vigilant for scurvy, even in non-traditional contexts.
- Awareness of social determinants of health is vital for diagnosing forgotten diseases like scurvy.
Related Concept Videos
Vitamins
1.7K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
1.7K
Ethics in Research
25.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.0K
Metabolic States of the Body: Fasting and Starvation
2.2K
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
2.2K
Fungal Phylum Microsporidia
242
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
242
Endocarditis II: Clinical Features of Infective Endocarditis
116
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
116
Retroviruses
13.3K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
13.3K

