Related Experiment Video
Updated: Nov 12, 2025
07:50
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Published on: January 7, 2019
7.1K
Temporal Trends of Infective Endocarditis in Olmsted County, Minnesota, Between 1970 and 2018: A Population-Based
Daniel C DeSimone1,2, Brian D Lahr3, Nandan S Anavekar2
1Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Open Forum Infectious Diseases
|March 17, 2021
Summary
Infective endocarditis (IE) incidence, particularly enterococcal IE, rose over time. Staphylococcus aureus IE showed seasonal patterns, but viridans group streptococci IE remained stable post-guideline changes.
Area of Science:
- Epidemiology
- Infectious Diseases
- Cardiology
Background:
- Infective endocarditis (IE) is a serious infection with potential for significant morbidity and mortality.
- Understanding temporal and seasonal variations in IE incidence is crucial for public health planning and resource allocation.
Purpose of the Study:
- To investigate long-term temporal and seasonal trends in infective endocarditis (IE) incidence.
- To analyze changes in IE incidence by causative pathogen and in relation to prevention guidelines.
Main Methods:
- Population-based study in Olmsted County, Minnesota (1970-2018).
- Review of all adult cases of definite or possible IE using the Rochester Epidemiology Project.
- Poisson regression analysis to assess trends in incidence, considering age, sex, calendar time, and season.
Main Results:
- Overall IE incidence was 7.9 cases per 100,000 person-years, with a significant increase over the 49-year study period.
- Enterococcal IE showed the most substantial increase over time.
- Staphylococcus aureus IE incidence exhibited seasonal variation, predominantly increasing in winter months.
Conclusions:
- Infective endocarditis incidence, especially due to Enterococcus species, has increased over time.
- Staphylococcus aureus IE demonstrates a seasonal dependency, while viridans group streptococci IE incidence remained stable.
- No significant change in viridans group streptococci IE incidence was observed following the 2007 AHA guidelines.
Keywords:
Staphylococcus aureusdental prophylaxisenterococciguidelinesincidenceinfective endocarditistrendsviridans group streptococciMore Related Videos
08:25Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
9.3K
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
24.5K
Related Concept Videos
01:25Endocarditis I: Introduction
138
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
138
01:25Endocarditis II: Clinical Features of Infective Endocarditis
116
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
116
01:29Endocarditis IV: Nursing Management
130
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
130
01:18Endocarditis III: Medical Management
86
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
86
01:18Steps in Outbreak Investigation
315
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
315
01:26Factors Affecting the Risk of Infection
13.0K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.0K