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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Beyond the Central Dogma: Bringing Epigenetics into the Classroom.

Dina Drits-Esser1, Molly Malone2, Nicola C Barber3

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Summary

This study introduces an epigenetics curriculum module for high school and undergraduate students. The module explores environmental influences on gene expression and student learning gains.

Keywords:
DNAEpigeneticscurriculumgeneticsinstructiontechnology

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Area of Science:

  • Genetics and Molecular Biology
  • Educational Science

Background:

  • Epigenetics investigates how environmental factors and cellular signals alter DNA packaging and gene expression.
  • Understanding epigenetics is crucial for grasping gene expression complexities and environmental influences.

Purpose of the Study:

  • To introduce epigenetics to high school and undergraduate students.
  • To provide educators with a supplemental curriculum module for teaching epigenetics.

Main Methods:

  • Development of a supplemental curriculum module by the Genetic Science Learning Center (GSLC).
  • Inclusion of online and paper-based activities covering introductory and advanced epigenetics topics.
  • Strategies for incorporating concepts like cell memory, epigenetic inheritance, nutrition, and behavior-epigenome connections.

Main Results:

  • The GSLC epigenetics module has been utilized in educational settings.
  • Student learning gains have been assessed.
  • The module aligns with Next Generation Science Standards.

Conclusions:

  • The GSLC epigenetics module effectively introduces complex epigenetic concepts to students.
  • The curriculum facilitates understanding of environmental impacts on gene expression and related phenomena.
  • The module supports science education standards and demonstrates measurable student learning outcomes.