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Kidney involvement in coronavirus-associated diseases (Review)
Zhicai Feng1, Yuqing Chen2, Yuqin Wu3
1Department of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
Experimental and Therapeutic Medicine
|March 18, 2021
Summary
Coronaviruses like SARS, MERS, and COVID-19 can cause kidney injury, worsening patient outcomes. This review summarizes coronavirus-kidney interactions to guide future therapies.
Area of Science:
- Virology
- Nephrology
- Infectious Diseases
Background:
- Coronaviruses have caused significant global pandemics since 2003, including SARS, MERS, and COVID-19.
- Emerging evidence links coronavirus infections to kidney injury, potentially worsening patient prognosis.
- Future coronavirus outbreaks are predicted, necessitating a better understanding of their impact on renal health.
Purpose of the Study:
- To systematically review current knowledge on coronaviruses.
- To elucidate the relationship between coronavirus infection and kidney injury.
- To summarize therapeutic strategies for coronavirus-associated kidney injury.
Main Methods:
- Systematic literature review.
- Analysis of clinical and autopsy findings.
- Synthesis of existing data on coronavirus nephropathy.
Main Results:
- Coronaviruses pose a continued threat due to potential for novel outbreaks.
- Kidney injury is a significant complication in patients with coronavirus infections.
- Understanding kidney involvement is crucial for developing effective treatments.
Conclusions:
- Coronaviruses can lead to severe kidney complications.
- Further research into coronavirus-induced kidney injury is essential.
- Improved therapeutic strategies are needed to manage coronavirus infections and protect renal function.
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