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Updated: Nov 12, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

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Left ventricular hypertrophy and other cardiac risk factors in migraineurs

Nina Zaproudina1,2, Teemu J Niiranen3,4, Verneri Anttila5,6,7

  • 1Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.

Acta Neurologica Scandinavica
|March 18, 2021
PubMed

Insights

Migraine is linked to cardiovascular risks like high blood pressure and left ventricular hypertrophy. These findings suggest a potential role for left ventricular hypertrophy in the connection between migraine and cardiovascular events.

Area of Science:

  • Cardiology
  • Neurology
  • Epidemiology

Background:

  • The relationship between cardiovascular risk factors and cardiovascular diseases in individuals with migraine is not fully understood.
  • Existing research requires further investigation into the specific mechanisms linking migraine to cardiovascular health.

Purpose of the Study:

  • To investigate the associations between migraine and various cardiovascular risk factors.
  • To explore novel cardiovascular risk predictors in the context of migraine.

Main Methods:

  • Utilized data from the Finnish Health 2000 Survey (BRIF8901), including 5737 adults aged 30+.
  • Analyzed 488 participants reporting migraine using logistic regression.
  • Included conventional cardiovascular risk factors, educational attainment, left ventricular hypertrophy, and hemoglobin A1c in the analysis.

Main Results:

  • Migraine was associated with female sex (OR=3.75), lower age (B=0.99), lower high-density lipoprotein cholesterol (OR=1.23), higher diastolic blood pressure (OR=1.31), and left ventricular hypertrophy (OR=1.32).
  • The likelihood of left ventricular hypertrophy increased with migraine frequency.

Conclusions:

  • Left ventricular hypertrophy may mediate the link between migraine and cardiovascular events, potentially due to migraine-related hypertension and dyslipidemia.
  • Further research is warranted to confirm these findings and elucidate the underlying mechanisms.
Abstract

Keywords:
cardiaccardiovascular risksepidemiologyheadachemigraine

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