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Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

184
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
184
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

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Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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Hypertension I: Introduction01:28

Hypertension I: Introduction

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Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
311
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

313
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
313
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

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Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
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Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

146
The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
146

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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Hypertension: Current trends and future perspectives.

Paul G Hunter1, Fiona A Chapman1, Neeraj Dhaun1

  • 1Department of Renal Medicine, Royal Infirmary of Edinburgh & University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, UK.

British Journal of Clinical Pharmacology
|March 18, 2021
PubMed
Summary
This summary is machine-generated.

Hypertension remains a major global health challenge, with many patients lacking adequate blood pressure control. New strategies, including novel medications and personalized medicine, are crucial for improving cardiovascular outcomes and managing this widespread condition.

Keywords:
diabeteshypertensionkidney diseasetreatments

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Area of Science:

  • Cardiology
  • Nephrology
  • Endocrinology

Background:

  • Hypertension is a growing global health concern, significantly contributing to cardiovascular disease and premature death.
  • It is closely linked with chronic kidney disease, diabetes mellitus, and obesity, exacerbating health risks.
  • Current management strategies often fail to achieve optimal blood pressure control in many patients.

Purpose of the Study:

  • To highlight the urgent need for improved blood pressure control in hypertension management.
  • To explore current and emerging therapeutic strategies for hypertension.
  • To discuss the potential of personalized medicine in revolutionizing hypertension treatment.

Main Methods:

  • Review of existing antihypertensive agents and their effective utilization.
  • Evaluation of treatments for co-existing conditions with blood pressure-lowering benefits, such as SGLT2 inhibitors.
  • Exploration of novel therapeutic agents targeting alternative prohypertensive pathways.
  • Investigation of non-pharmacological strategies like immunotherapy.
  • Consideration of advancements in genomics and molecular modification for personalized medicine.

Main Results:

  • Despite existing treatments, achieving adequate blood pressure control remains a challenge for many hypertensive patients.
  • Rising rates of hypertension-related cardiovascular mortality correlate with increasing prevalence of CKD, diabetes, and obesity.
  • Novel agents like dual angiotensin receptor-neprilysin inhibitors and non-pharmacological approaches show promise.
  • Personalized medicine, driven by genomic and molecular advancements, offers future revolutionary potential.

Conclusions:

  • Improving blood pressure control is a critical priority in global health.
  • A multi-faceted approach combining optimized existing therapies, novel agents, and non-pharmacological strategies is necessary.
  • Personalized medicine holds significant promise for transforming hypertension management and improving cardiovascular protection.