Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Propagation of Action Potentials01:23

Propagation of Action Potentials

7.9K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
7.9K
Relationship Formation02:12

Relationship Formation

43.5K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
43.5K
Activation and Inactivation of G Proteins01:22

Activation and Inactivation of G Proteins

8.6K
Heterotrimeric G proteins are guanine nucleotide-binding proteins. As the name suggests, heterotrimeric G proteins are composed of three subunits: alpha, beta, and gamma. They remain GDP-bound or GTP-bound inside the cells and switch between inactive/active states. The Gα subunit possesses the nucleotide-binding pocket that binds guanine nucleotides and switches between GDP or GTP-bound states. In contrast, the Gꞵ and Gγ subunits are always bound together with high...
8.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Benchmarking fMRI Denoising Pipelines.

Human brain mapping·2026
Same author

Human striatal population state dynamics.

bioRxiv : the preprint server for biology·2026
Same author

Dynamic Brain States With Cannabis Intoxication: Beyond "More Is Better" in Interpreting Brain Connectivity.

Biological psychiatry·2026
Same author

Digital phenotyping of affect and stress in emerging adults.

Frontiers in digital health·2026
Same author

Bidirectional relations between avoidant coping and dependent stressors in college students.

Anxiety, stress, and coping·2026
Same author

Functional Magnetic Resonance Imaging Signal Typically Viewed as "Noise" Has Clinical Relevance in Psychiatry.

Biological psychiatry global open science·2026
Same journal

On the clinical anatomy of technological cognition.

Cognitive neuroscience·2026
Same journal

Increasing statistical power in functional MRI through permutation and multivariate statistics.

Cognitive neuroscience·2026
Same journal

fMRI research: do we need statistically better studies, larger studies, or no more studies?

Cognitive neuroscience·2026
Same journal

Catching the drift: EEG microstate dynamics resemble time-on-task changes in mind wandering and sustained attention.

Cognitive neuroscience·2026
Same journal

Toward a cognitive neuroscience of technology.

Cognitive neuroscience·2026
Same journal

What behavioral relevance is (not).

Cognitive neuroscience·2026
See all related articles

Related Experiment Video

Updated: Nov 12, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.3K

Sex differences in functional network dynamics observed using coactivation pattern analysis.

Laura Murray1,2, J Michael Maurer1,2,3, Alyssa L Peechatka1,2

  • 1McLean Imaging Center, McLean Hospital, Belmont, Massachusetts, USA.

Cognitive Neuroscience
|March 18, 2021
PubMed
Summary
This summary is machine-generated.

Males and females exhibit distinct brain network dynamics during rest. These sex differences involve unique patterns of time spent in, and transitions between, specific brain states, particularly attention networks.

Keywords:
Sex differencescoactivation pattern analysisfunctional magnetic resonance imagingfunctional network dynamicshuman connectome projectresting-state

More Related Videos

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.8K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.5K

Related Experiment Videos

Last Updated: Nov 12, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.3K
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.8K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.5K

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Traditional static functional connectivity measures reveal sex differences in brain organization.
  • Dynamic functional connectivity analysis offers novel insights into temporal brain network changes and neurobiological sex differences.

Purpose of the Study:

  • To investigate sex differences in dynamic brain network organization using Coactivation Pattern Analysis (CAP).
  • To explore sex-specific temporal patterns and state transitions in large-scale brain networks during rest.

Main Methods:

  • Resting-state functional magnetic resonance imaging (rs-fMRI) data from 362 participants (181 males, 181 females) from the Human Connectome Project.
  • Coactivation Pattern Analysis (CAP) to identify transient network states (TNSs) and analyze state transitions.
  • Comparison of time spent in TNSs and frequency of state transitions between sexes across two imaging sessions.

Main Results:

  • Significant sex differences were observed in time spent in specific TNSs and state transition patterns.
  • Females spent more time in TNSs associated with the dorsal attention and occipital/sensory-motor networks, with more frequent transitions into these states.
  • Males spent more time in TNSs associated with the salience network, with longer durations within these states. Sex-specific transition patterns from the default mode network (DMN) to attention networks were identified.

Conclusions:

  • Males and females exhibit distinct dynamic brain network organization at rest, particularly in attention-related networks.
  • Sex-specific temporal dynamics and transition patterns between brain states suggest underlying neurobiological differences.
  • These findings provide a foundation for exploring the cognitive and behavioral implications of sex-specific brain network dynamics.