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Updated: Nov 12, 2025

09:55
An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
Published on: April 23, 2018
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[Intra-oral Perineurioma, a case report]
Nederlands Tijdschrift Voor Tandheelkunde
|March 18, 2021
Summary
A rare soft tissue perineurioma tumor was found in a 48-year-old woman's cheek. This slow-growing, asymptomatic mass was successfully removed via excisional biopsy.
Area of Science:
- Oral and Maxillofacial Surgery
- Surgical Pathology
- Oncology
Background:
- Perineuromas are rare, benign nerve sheath tumors.
- Intra-oral presentations are exceptionally uncommon, posing diagnostic challenges.
- Slow-growing, asymptomatic masses require careful evaluation.
Observation:
- A 48-year-old female presented with a 3-year history of a slow-growing, asymptomatic intra-oral mass.
- A 5 cm well-defined tumor was located in the right cheek, with intact overlying mucosa and skin.
- Magnetic Resonance Imaging (MRI) suggested a solitary mass with benign features.
Findings:
- Histopathological examination confirmed a soft tissue perineurioma.
- The tumor exhibited benign characteristics on imaging and pathology.
- Surgical excision was the chosen treatment modality.
Implications:
- This case highlights the importance of considering rare soft tissue tumors in the differential diagnosis of intra-oral masses.
- Accurate histopathological diagnosis is crucial for appropriate management of perineuromas.
- Early detection and surgical management can lead to favorable outcomes for benign intra-oral tumors.

