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Updated: Nov 12, 2025

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
Published on: June 8, 2014
[Epidemiology of osteoporosis]
1Département de rhumatologie, centre hospitalier régional d'Orléans, université d'Orléans, EA 4708 - I3MTO Orléans, France.
Abstract:
Epidemiology of osteoporosis. Fragility fractures associated with osteoporosis have become increasingly common in women as early as age 55 and in men after age 65. These fractures cause substantial morbidity but also excess mortality and increasing health costs. The number of people aged 50 and over at high risk of fracture worldwide was estimated in 2010 at 158 million, and this number could double by 2040. In Europe, the total number of fragility fractures was 2.7 million in 2017 and could reach 3.3 million in 2030. Osteoporosis management is not optimal. There is a growing gap between the percentage of patients eligible for treatment and the percentage of patients treated. In France, even among patients who have had a fracture, the percentage of patients receiving treatment in the following year is less than 20%.
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