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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Nov 12, 2025

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

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Published on: June 9, 2016

Single-Sided Magnetic Particle Imaging Device with Field-Free-Line Geometry for in-vivo Imaging Applications.

Jason Pagan¹, Chris McDonough¹, Triet Vo²

¹Physics Department, University of Massachusetts Boston, Boston, MA 02125 USA.

IEEE Transactions on Magnetics

|March 22, 2021

Summary

This summary is machine-generated.

Magnetic Particle Imaging (MPI) offers superior in vivo imaging. A new single-sided MPI device with a field-free line geometry achieves higher signal for small animal and human imaging.

Keywords:

Magnetic particle imaging (MPI)field-free line (FFL)in-vivo imaging magnetic nanoparticles single-sided device

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Area of Science:

Medical Imaging
Biophysics
Nanotechnology

Background:

Magnetic Particle Imaging (MPI) shows potential for advanced in vivo imaging.
Clinical translation is limited by challenges in scaling selection field coils for human imaging, leading to safety and power concerns.

Purpose of the Study:

To develop an alternative MPI topology addressing scalability and power issues.
To introduce a novel single-sided MPI device with a field-free line geometry.

Main Methods:

Designed and constructed a prototype single-sided MPI device.
Implemented a field-free line geometry instead of a field-free point.
Characterized the device for in vivo imaging applications.

Main Results:

The single-sided topology accommodates larger subjects and reduces hardware complexity.
The field-free line geometry offers a potential tenfold signal increase compared to field-free point systems.
The device is suitable for in vivo imaging of small animals and human regions of interest.

Conclusions:

The developed single-sided MPI device with field-free line geometry is a promising advancement for clinical applications.
This approach overcomes key limitations of traditional MPI systems, enabling broader in vivo imaging possibilities.
Further research and development could lead to widespread clinical adoption of this technology.