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Updated: Nov 12, 2025

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

Protocol for transgenerational learned pathogen avoidance behavior assays in Caenorhabditis elegans.

Rebecca S Moore¹, Rachel Kaletsky^1,2, Coleen T Murphy^1,2

¹Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

|March 22, 2021

Summary

Learned behaviors can be inherited across generations via epigenetic mechanisms. This study demonstrates a method in Caenorhabditis elegans to induce transgenerational memory of pathogen avoidance in four progeny generations.

Failed At:

2026-06-19T13:28:46.234078+00:00

Keywords:

Genetics Model organisms

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