Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Apparent Weight01:09

Apparent Weight

9.3K
True weight is the measure of the gravitational force acting on an object. However, if the object accelerates, its measured weight is different from its true weight. Similar observations can be made when the object is submerged in water. An object's weight in water is its apparent weight, which is equal to the difference between its true weight and the buoyant forces.
Consider a person standing on a bathroom scale inside an elevator. If the scale is accurate at rest, its reading equals the...
9.3K
ATP Yield01:31

ATP Yield

76.1K
Cellular respiration produces 30 - 32 ATP per glucose molecule. Although most of the ATP results from oxidative phosphorylation and the electron transport chain (ETC), 4 ATP are gained beforehand (2 from glycolysis and 2 from the citric acid cycle).
The ETC is embedded in the inner mitochondrial membrane and is comprised of four main protein complexes and an ATP synthase. NADH and FADH2 pass electrons to these complexes, which pump protons into the intermembrane space. This distribution of...
76.1K
Data Reporting and Recording01:24

Data Reporting and Recording

5.1K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.1K
Turnover Number and Catalytic Efficiency01:19

Turnover Number and Catalytic Efficiency

17.6K
The turnover number of an enzyme is the maximum number of substrate molecules it can transform per unit time. Turnover numbers for most enzymes range from 1 to 1000 molecules per second. Catalase has the known highest turnover number, capable of converting up to 2.8×106 molecules of hydrogen peroxide into water and oxygen per second. Lysozyme has the lowest known turnover number of half a molecule per second.
Chymotrypsin is a pancreatic enzyme that breaks down proteins during digestion....
17.6K
Arrhenius Plots02:34

Arrhenius Plots

43.6K
The Arrhenius equation relates the activation energy and the rate constant, k, for chemical reactions. In the Arrhenius equation, k = Ae−Ea/RT, R is the ideal gas constant, which has a value of 8.314 J/mol·K, T is the temperature on the kelvin scale, Ea is the activation energy in J/mole, e is the constant 2.7183, and A is a constant called the frequency factor, which is related to the frequency of collisions and the orientation of the reacting molecules.
The Arrhenius equation can be used...
43.6K
Pivot Bearings01:23

Pivot Bearings

1.7K
In mechanical systems, bearings are crucial in facilitating relative motion between two components while minimizing friction and wear. They help distribute various loads (radial, axial or a combination of both loads) across machinery parts, ensuring smooth and efficient operation.
A pivot bearing is a specialized type of bearing designed to support axial loads on a rotating shaft. The bearing surface, or the pivot, is positioned at the end of a shaft to support the axial thrust. The pivot may...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combination sclerotherapy and band ligation for refractory transfusion-dependent nodular gastric antral vascular ectasia (GAVE): inducing submucosal scarring.

Clinical journal of gastroenterology·2026
Same author

Safety of biologics and Janus kinase inhibitors in inflammatory bowel disease patients with low cardiovascular risk.

Crohn's & colitis 360·2026
Same author

ChEA-KG and ChEA-KG-TS: a network-based transcription factor enrichment analysis tool with an accompanying time-series workflow.

Nucleic acids research·2026
Same author

Performance of a large language model on the reasoning tasks of a physician.

Science (New York, N.Y.)·2026
Same author

A tool based on objective data to identify patients at elevated risk of hospital-onset <i>Staphylococcus aureus</i> bacteremia: a nested case-control study.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026
Same author

The Common Fund Data Ecosystem (CFDE).

bioRxiv : the preprint server for biology·2026
Same journal

Zero-shot reconstruction of mutant spatial transcriptomes.

Patterns (New York, N.Y.)·2026
Same journal

Dendritic nonlinearities mitigate communication costs.

Patterns (New York, N.Y.)·2026
Same journal

Erratum: Agentic AI as a coordination paradigm in digital health and agri-food systems.

Patterns (New York, N.Y.)·2026
Same journal

Spacing effect improves generalization in biological and artificial systems.

Patterns (New York, N.Y.)·2026
Same journal

A multi-modal foundation model for brain disease diagnosis and medical imaging.

Patterns (New York, N.Y.)·2026
Same journal

DuoMod-Net: Logarithmic balancing and geometric refinement for imbalanced semi-supervised medical image segmentation.

Patterns (New York, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Nov 12, 2025

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

15.7K

Appyters: Turning Jupyter Notebooks into data-driven web apps.

Daniel J B Clarke1, Minji Jeon1, Daniel J Stein1

  • 1Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA.

Patterns (New York, N.Y.)
|March 22, 2021
PubMed
Summary
This summary is machine-generated.

Appyters transform Jupyter Notebooks into standalone web applications for bioinformatics. This innovation makes complex data analysis accessible without coding, streamlining research and application development.

Keywords:
RNA-seqTCGAbig datadata analysisdata visualizationgene set enrichment analysismachine learningnotebooksscRNA-seqworkflow

More Related Videos

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects
06:36

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects

Published on: October 18, 2024

1.2K
Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes
08:26

Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes

Published on: November 23, 2021

2.8K

Related Experiment Videos

Last Updated: Nov 12, 2025

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

15.7K
Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects
06:36

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects

Published on: October 18, 2024

1.2K
Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes
08:26

Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes

Published on: November 23, 2021

2.8K

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Data Science

Background:

  • Jupyter Notebooks facilitate data analysis pipelines with code, text, and visualizations.
  • There is a need for more accessible, user-friendly tools in bioinformatics research.

Purpose of the Study:

  • To extend Jupyter Notebooks for broader accessibility.
  • To create standalone, web-based bioinformatics applications from notebooks.

Main Methods:

  • Developed Appyters, a system that converts Jupyter Notebooks into web applications.
  • Implemented user-friendly forms for data upload and parameter setting.
  • Enabled cloud-based execution of notebooks without direct user coding.

Main Results:

  • Created numerous reusable bioinformatics workflows as Appyters.
  • Applications include machine learning pipelines, omics data analysis, and figure generation.
  • Appyters are available via the Appyters Catalog.

Conclusions:

  • Appyters enable rapid development of interactive web-based bioinformatics applications.
  • This approach enhances the accessibility and usability of complex data analysis tools.