Recent Advances of Molecularly Imprinted Polymers Based on Cyclodextrin

Area of Science:

• Supramolecular Chemistry
• Polymer Science
• Analytical Chemistry

Background:

• Molecular imprinting polymers (MIPs) are artificial receptors with specific binding sites.
• Cyclodextrins (CDs) are supramolecular compounds with unique structural properties suitable for MIPs.
• CDs can act as functional monomers or carrier modifiers in MIP development.

Purpose of the Study:

• To review recent advances in cyclodextrin-based molecular imprinting polymers (CD-MIPs) over the past five years.
• To discuss the diverse roles of CDs in MIP construction.
• To focus on the applications of CD-MIPs in sample preparation, detection, sensing, and drug delivery.

Main Methods:

• Literature review of scientific publications from the last five years.
• Categorization of CD-MIPs based on the role of CDs (e.g., functional monomer, carrier modifier).
• Analysis of applications in sample preparation, detection, sensing, and drug delivery.

Main Results:

• CDs significantly enhance the specificity and efficiency of MIPs.
• CD-MIPs have shown promising results in various analytical and biomedical applications.
• Recent advancements include novel designs and improved performance metrics for CD-MIPs.

Conclusions:

• CD-based MIPs represent a powerful tool for molecular recognition.
• Further research is needed to overcome current challenges and explore future prospects.
• CD-MIPs hold great potential for advanced applications in various scientific fields.