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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Interdisciplinary approach to endogenous neonatal endophthalmitis. Case report]
Matías Osaba1,2, Alejandro Del Rivero3, Tatiana Canchi4,2
1Instituto de la Visión Cerro, Sanatorio Allende, sede Cerro, Córdoba, Argentina. doctorosaba@gmail.com.
Neonatal endogenous endophthalmitis is rare but serious, affecting premature infants with complications like sepsis. Early detection and interdisciplinary care are crucial for preserving visual health in these vulnerable newborns.
Area of Science:
- Ophthalmology
- Neonatology
- Pediatric Infectious Diseases
Background:
- Neonatal endogenous endophthalmitis is a rare but severe ocular infection in newborns.
- It often presents in premature infants with significant comorbidities, including low birth weight, surgical complications, and sepsis.
- Prompt diagnosis and management are critical to prevent irreversible vision loss.
Observation:
- This case report details a preterm infant with a history of multiple abdominal surgeries.
- The infant developed sepsis, meningitis, and subsequently, neonatal endogenous endophthalmitis.
- The patient's complex medical history and comorbidities contributed to the development of the infection.
Findings:
- The case highlights the extremely low frequency of endogenous endophthalmitis in neonates.
- Sepsis and meningitis were identified as preceding conditions that likely facilitated the ocular infection.
- The clinical presentation and diagnostic challenges associated with this rare condition were observed.
Implications:
- This case underscores the importance of vigilant monitoring for ocular complications in critically ill neonates.
- An interdisciplinary approach involving neonatology, infectious disease, and ophthalmology is vital for optimal patient outcomes.
- Preserving visual health in neonates with endogenous endophthalmitis requires timely and coordinated medical intervention.
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