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Resurrected Ancestors Reveal Origins of Metamorphism in XCL1
Patricia J LiWang1, Lee-Ping Wang2, Andy LiWang3
1Department of Molecular and Cell Biology, University of California, Merced, CA 95343, USA.
Trends in Biochemical Sciences
|March 23, 2021
Abstract:
In a recent study, Dishman et al. resurrected ancestors of the metamorphic chemokine, XCL1, inferred through phylogenetics, and found that metamorphism arose in the XCL1 lineage ~150 million years ago. A zigzagging evolutionary path suggests that the metamorphic properties are adaptive and reveals three design principles that could be used for technological applications.
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