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Journal bearings are mechanical components that support and provide lateral stability to rotating shafts and axles. They are crucial in reducing friction, wear, and vibration in machinery such as engines, turbines, and pumps. The principle behind journal bearings is forming a thin lubricant film between the bearing surface and the rotating shaft, which minimizes direct contact and reduces frictional forces.
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Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.
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Brenna L Morse1

  • 1By Brenna L. Morse, PhD, RN, NCSN, CNE, Solomont School of Nursing, Zuckerberg College of Health Sciences, University of Massachusetts Lowell, Lowell, MA, Brenna_Morse@UML.edu.

Nurse Educator
|March 23, 2021
PubMed
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No abstract available in PubMed .

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