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Updated: Nov 11, 2025

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
Published on: April 30, 2019
Emergence of self-organizational patterning at the mesoscopic scale
1Laboratory of Artificial and Natural Evolution (LANE), Department of Genetics and Evolution, University of Geneva, Sciences III, 30, Quai Ernest-Ansermet, 1211 Geneva 4, Switzerland; SIB Swiss Institute of Bioinformatics, Geneva, Switzerland.
Abstract:
In this issue of Developmental Cell, Chuyen et al. (2021) suggest that the Scf/Kit pathway controls mutual repulsion of multiciliated cells and their affinity for epidermal cell junctions through soluble and membrane-associated Scf ligands, respectively. Effective self-organizational patterning emerges at the mesoscopic scale as a small set of effective behaviors.

