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Light-addressable potentiometric sensor for biochemical systems
D G Hafeman1, J W Parce, H M McConnell
1Molecular Devices Corporation, Palo Alto, CA 94304.
Science (New York, N.Y.)
|May 27, 1988
Abstract:
Numerous biochemical reactions can be measured potentiometrically through changes in pH, redox potential, or transmembrane potential. An alternating photocurrent through an electrolyte-insulator-semiconductor interface provides a highly sensitive means to measure such potential changes. A spatially selectable photoresponse permits the determination of a multiplicity of chemical events with a single semiconductor device.