Related Experiment Video
Updated: Nov 11, 2025
06:23
Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
9.0K
Local lung coagulation post resection: an ex-vivo porcine model.
A Kirschbaum1, Th M Surowiec2, A Pehl3
1Department of Visceral, Thoracic and Vascular Surgery, University Hospital Marburg, Marburg, Germany. Kirschbaum001@gmx.de.
Lasers in Medical Science
|March 24, 2021
Summary
Additional laser coagulation after lung resection can reduce air leakage. This study found that ventilating the resection area after using a Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) laser significantly decreased air loss in porcine lung models.
Area of Science:
- Thoracic Surgery
- Laser Medicine
- Pulmonary Research
Background:
- Non-anatomical lung resections using Nd:YAG lasers create coagulated surfaces.
- Air leakage can occur from these surfaces once ventilation begins.
Purpose of the Study:
- To evaluate the sealing effect of additional laser coagulation on lung resection surfaces.
- To determine if coagulation before or after ventilation offers improved air leakage reduction.
Main Methods:
- Porcine lung blocks underwent non-anatomical resection with a Nd:YAG laser.
- Three groups were studied: control, coagulation without ventilation, and coagulation with ventilation.
- Air leakage was measured, and coagulation layer thickness was histologically analyzed.
Main Results:
- The control group (no additional coagulation) showed significant air leakage.
- Additional coagulation without ventilation showed minimal reduction in air leakage.
- Coagulation performed after restarting ventilation significantly reduced air leakage and increased coagulation layer thickness.
Conclusions:
- Additional coagulation of the ventilated resection area after non-anatomical lung resection with a Nd:YAG laser can effectively reduce air leakage.
- This technique enhances the sealing of the lung parenchyma.
- Further investigation in clinical settings may be warranted.
