Hyperbaric oxygen therapy acts as an alternative method in treating injection-induced nodules

Area of Science:

• Dermatology
• Experimental Therapeutics

Background:

• Cosmetic injection-induced nodules present clinical challenges.
• Foreign body granulomas are a common cause of persistent nodules.

Observation:

• A patient developed multiple neck nodules post-mesotherapy, diagnosed as foreign body granulomas via biopsy.
• Standard treatments like surgery or steroids were declined by the patient.

Findings:

• The patient underwent experimental hyperbaric oxygen therapy (HOT).
• After one month, ultrasound revealed significantly reduced nodule hardness and increased local blood flow.
• Complete nodule elimination was not achieved, but notable improvement was observed.

Implications:

• Hyperbaric oxygen therapy (HOT) may offer a viable alternative for managing injection-induced nodules.
• Further research is warranted to establish the efficacy and safety of HOT for this condition.