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Updated: Nov 11, 2025

Perspectives on Neuroscience
Published on: July 31, 2007
Epistemological reflections on chances and borders of "biological psychiatry"
Georg Juckel1, Paraskevi Mavrogiorgou1
1Department of Psychiatry, LWL University Hospital, Ruhr University Bochum, Bochum, Germany.
Objectives:
After decades of intensive research in the field of biological psychiatry and its partly modest and non-specific results, the self-critical question arises as to whether basic predispositions in epistemology and philosophy of science prevent bigger successes.
Methods/Results:
Central here are the arguments that the brain is unable to recognise itself completely and that the psychological mental level cannot be connected with the physiological neurobiological level in a causal way.
Conclusion:
In conclusion, for biological psychiatry it might be well advised to reflect on the research, diagnostics and treatment realistically achievable according to the theoretical framework, so that the impression of valid knowledge progress, although limited, remains motivating for our younger generation.
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