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Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop

Lu Bai1,2, Margaux Vienne3, Ling Tang1,2

  • 1Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Science (New York, N.Y.)
|March 26, 2021
PubMed
Summary

Adult mouse livers contain stem cells that develop into liver type 1 innate lymphoid cells (ILC1s). Interferon-gamma (IFN-γ) creates a feedback loop, promoting ILC1 development within the liver.

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